Home Active Agrochemical Ingredient New ISO Published – Bayer Candidate Nicofluprole in Phenylpyrazole Insecticides Class

New ISO Published – Bayer Candidate Nicofluprole in Phenylpyrazole Insecticides Class

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New ISO Published – Bayer Candidate Nicofluprole in Phenylpyrazole Insecticides Class

Phenylpyrazole insecticides are a class of chemically-related broad-spectrum insecticides. The chemical structures of these insecticides are characterized by a central pyrazole ring with a phenyl group attached to one of the nitrogen atoms of the pyrazole.

Phenylpyrazole insecticides were developed in response to increasing pesticide resistance to other chemicals. Now, along with neonicotinoids, they are some of the most widely-used pesticides.

Phenylpyrazole insecticides function by blocking glutamate-activated chloride channels in insects. Mammals do not have this type of chloride channel, making them much less susceptible to its effects. However, they do have the capacity to disrupt epithelial cells in human intestine and adversely impact human health.

Nicofluprole Molecule Details:

STATUS: ISO 1750 (provisionally approved)

IUPAC:  2-chloro-N-cyclopropyl-5-(1-{2,6-dichloro-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}-1H-pyrazol-4-yl)-N-methylpyridine-3-carboxamide

CAS REG. NO.:  1771741-86-6


Activity: insecticides (phenylpyrazole insecticides)

Patent information:

Bayer filed international patent for Nicofluprole compound protection in 2014, which is published in May 14, 2015. Patent Number: WO2015067646A1 having Indian Patent equivalents e.g. Indian IN 201617014488 and IN201617014851.

Bayer has filed six patent families out of two patent families are related to their process patents, e.g. WO2018104214A1 and WO2019243243A1.

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