In order to control weeds in rice in Asia, FMC Corporation and Syngenta Crop Protection have entered into a partnership. Tetflupyrolimet, the new active component, was discovered and developed by FMC for use in rice with assistance from Syngenta. It is the first significant herbicide with a unique mode of action in more than three decades (DHODH – HRAC Group 28), offering relief to farmers troubled by rising weed resistance to current herbicides.
Tetflupyrolimet Mode of Action
FMC Corporation , a leading agricultural sciences company, obtained a new mode of action classification for its proprietary herbicide molecule, tetflupyrolimet. It is the first active ingredient in the Herbicide Resistance Action Committee (HRAC) and Weed Science Society of America (WSSA) Group 28 and the first new herbicide with a novel mode of action in the crop protection industry in over three decades.
Agreement :- Under the agreement, FMC and Syngenta both will bring tetflupyrolimet-based products to key rice markets in Asia. FMC will register and commercialize tetflupyrolimet, as well as a broad array of tetflupyrolimet formulations for rice throughout Asia. In the China rice market, FMC will focus on mixtures only. Syngenta will register and commercialize the compound and an array of products in China for the rice market, while offering mixtures for use on rice in India, Vietnam, Indonesia, as well as in Japan and South Korea. Syngenta will also commercialize the compound for rice in Bangladesh.
In addition, FMC will register and commercialize tetflupyrolimet and a full portfolio of tetflupyrolimet formulations in markets globally for rice and other crops.
About Tetflupyrolimet
Tetflupyrolimet Structure
- Description :- Tetflupyrolimet is an N-alkylpyrrolidine that is pyrrolidine substituted by methyl, oxo, (2-fluorophenyl)aminocarbonyl, and 3-(trifluoromethyl)phenyl groups at positions 1, 2, 3, and 4, respectively. It is a herbicide developed by FMC Corporation for the control of grass weeds in rice, as well as key broadleaf weeds and sedges. It has a role as a herbicide, a pyrimidine synthesis inhibitor and an EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor. It is an anilide, a member of monofluorobenzenes, a secondary carboxamide, a member of (trifluoromethyl)benzenes, a N-alkylpyrrolidine and a pyrrolidinecarboxamide.
- Indication– Herbicide
- IUPAC– 3-Pyrrolidinecarboxamide, N-(2-fluorophenyl)-1-methyl-2-oxo-4-[3-(trifluoromethyl)phenyl]-, (3S, 4S)-
- CAS RN – 2053901-33-8
- Chemical Class – Anilide Herbicides
- Molecular Formula – C19H16F4N2O2
- Mode of Action – Stimulates Rna Synthesis. Absorbed Through Stems And Roots. No Herbicidal Activity Itself But Is Rapidly Hydrolysed To An Active Metabolite
“Tetflupyrolimet is a transformative herbicide that provides season-long control of important grass weeds with just one application in the growing season,” said Diane Allemang, FMC executive vice president and chief marketing officer. “Due to its new mode of action, tetflupyrolimet has no known cross-resistance and will provide millions of growers around the world with a critical weed management tool. It provides outstanding residual control with very low dose rates and an exceptional sustainability profile.”
Tetflupyrolimet enhances the yield and quality of rice production by controlling destructive grass weeds that compete with the crop for water, nutrients, light and space. In addition to being easy to apply in traditional transplanted rice, the herbicide is also highly suited to direct-seeded rice.
About FMC Corporation
FMC Corporation, an agricultural sciences company, provides innovative solutions to growers around the world with a robust product portfolio fueled by a market-driven discovery and development pipeline in crop protection, plant health, and professional pest and turf management. This powerful combination of advanced technologies includes leading insect control products based on Rynaxypyr® and Cyazypyr® active ingredients; Authority®, Boral®, Centium®, Command® and Gamit® branded herbicides; Talstar® and Hero® branded insecticides; and flutriafol-based fungicides. The FMC portfolio also includes biologicals such as Quartzo® and Presence® bionematicides. FMC Corporation employs approximately 6,400 employees around the globe.
FMC, the FMC logo, Rynaxypyr, Cyazypyr, Authority, Boral, Centium, Command, Gamit, Talstar, Hero, Quartzo and Presence are trademarks of FMC Corporation or an affiliate. Always read and follow all label directions, restrictions and precautions for use. Products listed here may not be registered for sale or use in all states, countries or jurisdictions. Hero® insecticide is a restricted use pesticide in the United States.
About Syngenta
Syngenta AG is a provider of agricultural science and technology, in particular seeds and pesticides with its management headquarters in Basel, Switzerland. It is owned by ChemChina, a Chinese state-owned enterprise
Syngenta was founded in 2000 by the merger of the agrichemical businesses of Novartis and AstraZeneca, and acquired by China National Chemical Corporation (ChemChina) in 2017. Its business units are Syngenta Crop Protection, Syngenta Seeds, Adama, and Syngenta Group China. In 2020, the Syngenta Group was formed, bringing together Syngenta, Adama, and the agricultural business of Sinochem under a single entity.
The 2011 Dow Jones Sustainability Index, named Syngenta one of the best performing chemical companies worldwide. However, the company has been controversial, mainly due to its main business – selling toxic chemicals and the environmental impact of those chemicals – but also due to its investment in lobbying. In 2012, the company was nominated for the Public Eye Award, which denounces companies with questionable human rights practices.
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