Insecticide Resistance Action Committee (IRAC) – Published New Mode of Action Classification – including Nematicides Mode of Action Classification – 2023

The Insecticide Resistance Action Committee published – Mode of Action (MOA) Classification Brochure 7th Edition, Version 7.2.

Insecticide Resistance Action Committee_IRAC_2023

IRAC Mode of Action (MOA) Classification Scheme, Version 10.3.

IRAC Poster Edition 10.4, December 2022. Based on the Mode of Action (MOA) Classification Version 10.4

IRAC-MOA-POSTER-2022-2023

Nematicide MoA Classification Version 2.1

Nematicide_Poster

Nematicide_Poster_2

Poster Notes:

  • Sub-group 3B: DDT is no longer used in agriculture and therefore this is only applicable for the control of insect vectors of human disease, such as mosquitoes, because of a lack of alternatives.
  • Sub-group10A: Hexythiazox is grouped with Clofentezine because they exhibit cross-resistance even though they are structurally distinct. Diflovidazin has been added to this group because it is a close analog of Clofentezine and is expected to have the same mode of action.
  • Group 20: While there is strong evidence that Bifenazate acts on the Qo site of Mitochondrial Complex III and some Bifenazate resistance mutations confer cross-resistance to Acequinocyl, the sites of action of Fluacrypyrim and Hydramethylnon have not been determined.
  • Groups 26 and 27 are unassigned.

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