March 20, 2021 – 4 more agrochemical candidates got published including Fenpyrazone (Kingagroot), Flumetylsulforim (ADAMA), Metarylpicoxamid (Corteva Fungicide), Rimisoxafen (FMC Herbicide). Please refer detail below
1.FENPYRAZONE
Fenpyrazone is the third generation of the HPPD inhibitor herbicides created by KingAgroot for corn planting. Due to its new chemical structure containing fluorine, compared with previous generations of HPPD inhibitors, Fenpyrazone has a more balanced herbicidal spectrum with a more stable effect. It has particularly excellent control effects on green foxtail, crabgrass, barnyard grass, goosegrass, etc. Fenpyrazone has no cross-resistance for green foxtail, crabgrass, barnyard grass, and the like, which are resistant to Nicosulfuron, and is very safe for corn crops. It is an excellent tool for the management of ALS inhibitor-resistant weeds.
In 2018, the patented herbicide compounds, Cypyrafluone and Bipyrazone of KingAgroot, applicable to wheat fields, were registered and introduced in the market. With the launch of new products in 2020, KingAgroot will provide weed resistance solutions for the planting of rice, corn, and wheat, which are the most important food crops in China and the world, in the next 20 years.
BASIC PRODUCT INFORMATION:
STATUS: ISO 1750 (provisionally approved)
IUPAC NAME: 4-{2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoyl}-1-ethyl-1H-pyrazol-5-yl 1,3-dimethyl-1H-pyrazole-4-carboxylate
CAS RN.: 1992017-55-6
ACTIVITY: herbicides (benzoylpyrazole herbicides)
Innovator: kingagroot chemical compounds co., ltd
Mechanism of Action (MoA): HPPD Inhibitor
Other Candidates from The Same Class: benzofenap; bipyrazone; cypyrafluone; fenpyrazone; pyrasulfotole; pyrazolynate; pyrazoxyfen; tolpyralate; topramezone; tripyrasulfone
IP Scenario:
1.CN105831123B; (WO2017177784A1; Est. Exp. March 15, 2037)
Title: Cornfield herbicidal composition and its application
Equivalents: BR112018071219A2; CN105831123A; CN105831123B; US10729133B2; US2019124925A1;WO2017177784A1
Indian Equivalents: IN201847039188
Abstract: The invention relates to cornfield herbicidal composition comprising pyrazolone compound and its application. The herbicidal composition comprises active ingredients A and B and safener compound C, wherein the active ingredient A has a general formula as shown in Claim 1, R1 = hydrogen atom, Me, etc., R2 = Me, Et, etc., R3 = ethoxy, 2-fluoroethoxy, etc., R4 = chlorine atom and Me, and R5, R6 and R7 are a hydrogen atom, alkyl, etc.; the active ingredient B = selected from triazines, nitriles, sulfonylurea, etc.; and the safener compound is selected from isoxadifen-Et, cyprosulfamide, mefenpyr-diethyl, etc. The inventive composition can effectively control Echinochloa crusgalli, Digitaria sanguinalis, Setaria viridis, and other weeds that have a wide weeding spectrum and reduced application amount and are safe for crops.
2.FLUMETYLSULFORIM
The compound is originally, covered in Dow patent published in 2014 (WO2014105845). Adama has filed 4 PCT patent applications including instant patent applications.
The said patent discloses the preparation of compounds and to the use of these compounds as fungicides. It also discloses methods of controlling a fungal disease such as Septoria tritici, comprising administering an effective amount of the fungicide compound to at least one surface associated with the plant, seed, or soil.
BASIC PRODUCT INFORMATION:
STATUS: ISO 1750 (provisionally approved)
IUPAC NAME: 5-fluoro-4-imino-3-methyl-1-[(4-methylphenyl)sulfonyl]-3,4-dihydropyrimidin-2(1H)-one
CAS RN.: 1616664-98-2
ACTIVITY: fungicides (Pyrimidine Fungicides)
Innovator: Adama Makhteshim Ltd.
Mechanism of Action (MoA): Possibly …
Other Candidates from The Same Class: bupirimate; diflumetorim; dimethirimol; ethirimol; fenarimol; ferimzone; flumetylsulforim; nuarimol; triarimol
IP Scenario:
1.WO2014105845A1 (Est. Exp. Dec 23, 2033)
Title: 3-Alkyl-5-fluoro-4-substituted-imino-3,4-dihydropyrimidin-2(1H)-one derivatives as fungicides
Assignee: Dow AgroSciences LLC, United States
Equivalents: AU2013370494A1; AU2013370494B2; BR102013033812A2; BR102013033812B1; CA2894553A1; CN105007737A; EP2953463A1; EP2953463A4; HK1215357A1; IL239597A; JP2016503816A; JP2019055959A; KR20150103174A; MX2015008565A; NZ708981A; NZ749557A; RU2015131832A; RU2644014C2; WO2014105845A1; US2015359225A1; US9642368B2; US2017240540A1; US10059703B2
Indian Equivalent: IN2015DN05350
Abstract: This present disclosure is related to the preparation of 3-alkyl-5-fluoro-4-substituted-imino-3,4-5 dihydropyrimidin-2(1H)-ones and their derivatives and to the use of these compounds as fungicides. Exemplary compound (I) was prepared (procedure given). Also provided are methods of controlling a fungal disease such as Septoria tritici, comprising administering an effective amount of the fungicide compound to at lease one surface associated with the plant, seed or soil.
3.METARYLPICOXAMID
BASIC PRODUCT INFORMATION:
STATUS: ISO 1750 (provisionally approved)
IUPAC NAME: (2S,3S)-3-(o-tolyl)butan-2-yl N-{[4-methoxy-3-(propanoyloxy)-2-pyridyl]carbonyl}-L-alaninate
CAS RN.: 2376209-11-7
ACTIVITY: fungicides (picolinamide fungicides)
Innovator: Corteva Agriscience
Mechanism of Action (MoA): Complex III or MET III electron transport inhibition, QiI (quinone inside Inhibition)
Other Candidates from The Same Class: fenpicoxamid; florylpicoxamid; metarylpicoxamid
IP Scenario:
1.WO2019173665 (Est. Exp. 2039-03-08)
Title: PICOLINAMIDES AS FUNGICIDES
Equivalents: AU2019231764A1; BR102019004480A2; CA3093446A1; CL2020002311A1; CN112040773A; CO2020012505A2; CR20200393A; EP3761790A1; KR20200129141A; US2019276404A1; US2020399222A1; UY38140A; WO2019173665A1
Abstract: This disclosure relates to picolinamides of Formula (I) and their use as fungicides.
4.RIMISOXAFEN
BASIC PRODUCT INFORMATION:
STATUS: ISO 1750 (provisionally approved)
IUPAC NAME: 5-chloro-2-{3-chloro-2-[3-(difluoromethyl)-1,2-oxazol-5-yl]phenoxy}pyrimidine
CAS RN.: 1801862-02-1
ACTIVITY: herbicides (oxazole herbicides)
Innovator: FMC Corporation.
Other Candidates from The Same Class: bixlozone; carboxazole; clomazone; fenoxasulfone; isouron; isoxaben; isoxachlortole; isoxaflutole; methiozolin; monisouron; pyroxasulfone; rimisoxafen; topramezone
IP Scenario:
1.WO2015108779 (Est. Exp.: 2035-01-09)
Title: Pyrimidinyloxy Benzene Derivatives as Herbicides
Equivalents: AR099122A1;AU2015206757A1;AU2019226283A1;BR112016016443B1;BR112016016443B8;CA2934891A1;CL2016001789A1;CN105916849A;CN105916849B;CN111574510A;DK3094631T3;EA030009B1;EA201691439A1;EP3094631A1;EP3094631B1;ES2719410T3;HUE044404T2;IL246373A;JP2017504624A;JP6541667B2;KR20160107276A;MD20160095A2;MX2016009163A;PE20161143A1;PL3094631T3;SG11201604813YA;SI3094631T1;TR201904712T4;TW201613876A;TWI669295B;US10131652B2;US10654840B2;US2016333000A1;US2019084972A1;US2020270238A1;UY35953A;WO2015108779A1
Indian Equivalents: IN201617021107
Abstract:
Disclosed are compounds of Formula (1), including all stereoisomers, N-oxides, and salts thereof, wherein Q, Z, R 2, R 3, and m are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula (1) and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.
