Nafoxametamide is a new γ-aminobutyric acid (GABA)-gated chloride channel allosteric modulator insecticide, developed by Shandong Chengchuang Lanhai Pharmaceutical Technology. This compound exhibits broad-spectrum activity against a variety of agricultural insect pests and acarids, with particularly high efficacy against Thrips palmi and Myzus persicae. Relative to currently available commercial insecticides, Nafoxametamide demonstrates enhanced insecticidal potency and an expanded target range. Furthermore, its synthetic route is characterized by operational simplicity, high yield, and favorable safety profiles. These attributes collectively indicate that Nafoxametamide possesses substantial potential for practical application in integrated pest management.
- Status: ISO (Provisionally Approved)
- IUPAC Name: 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[(methoxyamino)methylene]-1-naphthalenecarboxamide
- CAS RN.: 2922827-79-8
- Activity: Insecticides (Isoxazoline)
- Inchikey: ASDVQSREIKRZHG-UHFFFAOYSA-N
- Inchi: InChI=1S/C24H16ClF6N3O3/c1-36-33-12-32-21(35)19-7-6-18(16-4-2-3-5-17(16)19)20-11-22(37-34-20,24(29,30)31)13-8-14(23(26,27)28)10-15(25)9-13/h2-10,12H,11H2,1H3,(H,32,33,35)
Global Patent Protection
Shandong Chengchuang has filed an international patent application seeking protection for the active compound Nafoxametamide. Subject to national phase entries and grant, the resulting patents are expected to provide protection until 2043.
About Shandong Chengchuang Lanhai Pharmaceutical Technology Co. Ltd.
Shandong Chengchuang Lanhai Pharmaceutical Technology Co., Ltd., the dedicated R&D center of Shandong Chenghui Pharmaceutical Group, has expanded its capabilities in impurity standards and pharmaceutical method development to support the group’s API and CDMO pipeline in Shandong, China. Operating alongside sister company Shandong Chenghui Shuangda Pharmaceutical Co., Ltd., the subsidiary consolidates research resources in Jinan with manufacturing capacity in Dezhou, enhancing end-to-end delivery from early-stage development to GMP production.
For more detailed information on Nafoxametamide visit ChemRobotics AgroPat Ultimate Discovery Suite N Platform – ChemRobotics.com (Global Agrochemical Intelligence Database)
